NCI is collaborating with the International Agency for Research on Cancer (IARC) and investigators from North America, Western Europe, Korea, New Zealand, and other countries in A Consortium of Agricultural COHort studies (AGRICOH). AGRICOH comprises 28 cohorts from agricultural populations across six continents. All cohorts study health outcomes in relation to environmental and occupational exposures in agricultural settings, with the exception of three general population cohorts encompassing a significant number of agricultural populations or planning to oversample individuals in agricultural areas. The consortium is interested in identifying environmental and occupational exposures in agricultural settings associated with excess risk of chronic illnesses, including cancer, respiratory, neurologic and autoimmune diseases, and reproductive and allergic disorders, as well as identifying factors associated with decreased morbidity risk. Initial pooling projects are underway.