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T Cell Alternative p38 Activation Pathway – Rockville

Jonathan Ashwell

1 Collaborator(s)

Funding source

National Cancer Institute (NIH)
The goal is to determine if T cell p38 activation plays a role in cancer. We have shown that it's activation in human pancreatic cancer is highly predictive of clinical course. Moreover, we have generated a small molecule inhibitor of this pathway that retards tumor progression in mouse models of pancreatic cancer.

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